Preheat oven to 350 degrees. Spray a 9 x 5 loaf pan with non-stick cooking spray.
In a large bowl, mix well the pumpkin puree, eggs, water, vegetable oil, sugar and vanilla.
In a separate bowl, mix the flour and the rest of the ingredients.
Add the flour mixture to the pumpkin mixture and stir until moistened.
Pour the mixture into the greased loaf pan.
Bake at 350 for about 1 hour. (oven times may vary, check with toothpick)
Remove the bread from the oven and allow to cool in the pan for 10 minutes.